D44 Comparative effect of felodipine-er, amlodipine, and nifedipine-gits in ambulatory hypertensive patients

Nifedipine GITS Package Insert

A comparative crossover evaluation of amlodipine and nifedipine GITS before and after a missed dose: 48-h blood pressure profiles.

Despite good pharmacologic control of blood pressure (BP), the untoward effects of noncompliance and missed doses have become a matter of concern, evidenced by the high frequency of deviations from prescribed treatment. Missing one or more days of medication on these “drug holidays” can disrupt the steady level of the drug and lead to rebound reactions when the dose is suddenly stopped, and res...

Comparative Effect of Valsartan and Amlodipine on Serum Lipoproteins (LDL and HDL) Levels among Hypertensive Patients

Introduction: Hypertension is a modifiable risk factor for cardiovascular diseases and is associated with several metabolic disorders like dyslipidemia. Drugs that control blood pressure effectively can increase the potentially atherogenic serum low-density lipoprotein (LDL) cholesterol fraction and triglycerides. In view of the available literature, the present study was undertaken to compare ...

Effect of nifedipine and amlodipine on wound healing in rats.

The wound healing effect of two calcium channel blockers, nifedipine and amlodipine was studied in rats using incision and excision wound models. In incision wound, two straight paravertebral skin thickness incision were made and on tenth day skin tensile strength was measured by using continuous water flow technique. In excision wound, circular piece of skin excised in its full thickness and w...

Effect of amlodipine on cardiovascular events in hypertensive haemodialysis patients

BACKGROUND Hypertensive haemodialysis patients may be at a high risk for cardiovascular events. This study was undertaken to ascertain whether the calcium channel blocker amlodipine reduces mortality and cardiovascular events in these high-risk patients. METHODS We evaluated the effects of amlodipine on cardiovascular events in 251 hypertensive haemodialysis patients in an investigator-design...